Acanthosis nigricans
☆ 2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
اهو موهيندڙ ماڻهن ۾ عام آهي.
References
Acanthosis nigricans هڪ بنيادي حالت جو هڪ چمڙي جي ظاهر آهي. اهو اڪثر ڪري چمڙي جي ڳچيءَ ۾ ظاهر ٿئي ٿو جهڙوڪ ڳچيءَ، بغلن ۽ ڳچيءَ ۾، اڻ واضح ڪنارن سان مخملي اونداهي دٻن وانگر نظر اچن ٿا. اها حالت عام طور تي ذیابيطس ۽ انسولين جي مزاحمت سان ڳنڍيل آهي، پر نادر ڪيسن ۾، اهو جسم جي اندر سرطان ڏانهن اشارو ڪري سگهي ٿو. اهو شايد هارمون جي مسئلن جي ڪري يا مخصوص دوائن جهڙوڪ اسٽيرائڊس ۽ پيدائش جي ڪنٽرول گولن جي ڪري ظاهر ٿي سگھي ٿو.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) هڪ عام چمڙي جي حالت آهي جيڪا مختلف صحت جي مسئلن جهڙوڪ انسولين جي مزاحمت، ذیابيطس، موهپا، ڪجهه ڪينسر، هارمونل مسئلا، ۽ دوائن جي رد عمل سان ڳنڍيل آهي. AN جو علاج بنيادي صحت جي مسئلن کي حل ڪرڻ تي ڌيان ڏئي ٿو. شروعات ۾، ڊاڪٽر انسولين مزاحمتي سنڊروم جي نشانين جي چڪاس ڪندا آهن، جن ۾ موهپا، هاءِ ڪوليسٽرول، هاءِ بلڊ پريشر، ۽ ٽائپ 2 ذیابيطس شامل آهن. ڊاڪٽر اڪثر ڪري topical retinoids کي پهرين علاج جي چونڊ جي طور تي پيش ڪن ٿا، جيڪو چمڙي جي ٿلهي ۾ مدد ڪري سگهي ٿو. تنهن هوندي، اهي مڪمل طور تي چمڙي جي اونداهي کي پتو نه ٿا ڏين. ٻيا علاج جا اختيار (salicylic acid, podophyllin, urea, calcipotriol) پڻ بار بار ايپليڪيشن جي ضرورت آهي.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ سبب
اهو عام طور تي 40 سالن کان گهٽ عمر وارن ماڻهن ۾ ٿئي ٿو، جينياتي طور تي وراثت ۾ ملي سگهي ٿو ۽ موهپا يا انڊوڪرينوپيٿس سان جڙيل آهي، جهڙوڪ هائيپوتايرايډيزم، ايڪوميگالي، پولي سسٽڪ اووري جي بيماري، انسولين جي مزاحمتي ذیابيطس يا ڪشنگ جي بيماري.
○ علاج ― OTC دوائون
#40% urea cream